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使用所有可用且可能有效的抗真菌药物治疗严重白色念珠菌性全眼球炎:氟康唑、脂质体两性霉素B、卡泊芬净和伏立康唑。

Severe Candida albicans panophthalmitis treated with all available and potentially effective antifungal drugs: fluconazole, liposomal amphotericin B, caspofungin, and voriconazole.

作者信息

Manfredi Roberto, Sabbatani Sergio

机构信息

Department of Clinical and Experimental Medicine, Division of Infectious Diseases, University of Bologna 'Alma Mater Studiorum', S. Orsola-Malpighi Hospital, Bologna, Italy.

出版信息

Scand J Infect Dis. 2006;38(10):950-1. doi: 10.1080/00365540600617041.

Abstract

A severe case of Candida albicans panophthalmitis, probably prompted by an underlying diabetes mellitus, is reported. The course was prolonged (more than 16 weeks), although favourable after treatment with several antifungal agents, all with a predictable activity in this ocular complication and with proven susceptibility in the present case: fluconazole, liposomal amphotericin B, caspofungin, and voriconazole.

摘要

本文报告了一例严重的白色念珠菌性全眼球炎病例,可能由潜在的糖尿病引发。病程较长(超过16周),尽管在使用几种抗真菌药物治疗后情况有所好转,这些药物对这种眼部并发症均具有可预测的活性,且在本病例中已证实敏感:氟康唑、脂质体两性霉素B、卡泊芬净和伏立康唑。

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