Jaworsky C, Cirillo-Hyland V, Petrozzi J W, Lessin S R, Murphy G F
Department of Dermatology, University of Pennsylvania, Philadelphia 19104.
Arch Dermatol. 1990 Dec;126(12):1609-16. doi: 10.1001/archderm.126.12.1609.
Two cases of regressing atypical histiocytosis were studied. New findings reported include the presence of CD1 epitope on large atypical histiocytoid cells and apparent early lymph node involvement. Because regressing atypical histiocytosis may demonstrate aberrant thymic differentiation antigen expression and T-cell receptor gene rearrangements, initial lymph node involvement, and eventuation in conventional lymphoma in some cases, the alternative term regressing-phase anaplastic lymphoma is proposed as a more accurate designation for this entity.
对两例消退性非典型组织细胞增多症进行了研究。报告的新发现包括在大型非典型组织细胞样细胞上存在CD1表位以及明显的早期淋巴结受累。由于消退性非典型组织细胞增多症可能表现出异常的胸腺分化抗原表达和T细胞受体基因重排、初始淋巴结受累，且在某些情况下最终发展为传统淋巴瘤，因此建议使用替代术语“消退期间变性淋巴瘤”来更准确地命名这一实体。
