Czepko Ryszard, Kwinta Borys
Klinika Neurochirurgii Collegium Medium UJ w Krakowie.
Polim Med. 2006;36(2):3-9.
The transsphenoidal pituitary tumors surgery is often connected with intraoperative rhinorrhea. This complication might be serious if occurs again in the postoperative period. The aim of this study is to evaluate the sella reconstruction methods in patients with intraoperative rhinorrhea and comparing of their efficiency.
In the group of 259 consecutive cases operated on at the Neurosurgery Department in Cracow using the transsphenoidal approach, in 40 occured intraoperatively observed rhinorrhea. In the 26 cases we used Surgicel, artificial dura or fascia and Tissucol (I group), and in 14 TachoComb with Tissucol but in 5 also fascia or artificial dura (II group).
Out of the 26 patients from the I group (without TachoComb) in 5 cases occurred postoperatively rhinorrhea (3-36 days after surgery). 4 patients were reoperated, 1 patient died due to the meningitis. 2 patients suffered from the visual disturbances due to the sella overpacking (7,7%), what was visualized in the control imaging studies. In 14 cases from the II group in 2 postoperative rhinorrhea was observed (in the 7 and the 30 day after operation)--14,2%. There were no signs of meningitis, and no fatal cases. The visual disturbances as well as overpacking of the sella were not observed.
Using of the TachoComb in reconstructive surgery of the sella reduces the risk of the post operative CSF leak and eliminates the features of the sella overpacking and visual deterioration.
经蝶窦垂体瘤手术常伴有术中鼻漏。如果术后再次发生这种并发症,可能会很严重。本研究的目的是评估术中鼻漏患者的鞍区重建方法并比较其效果。
在克拉科夫神经外科采用经蝶窦入路连续手术的259例患者中,40例术中出现鼻漏。26例患者使用了速即纱、人工硬脑膜或筋膜以及纤维蛋白胶(I组),14例使用了速即纱和纤维蛋白胶,但其中5例还使用了筋膜或人工硬脑膜(II组)。
I组(未使用速即纱)的26例患者中,5例术后出现鼻漏(术后3 - 36天)。4例患者再次手术,1例患者因脑膜炎死亡。2例患者因鞍区填充过度出现视力障碍(7.7%),在对照影像学检查中可见。II组的14例患者中,2例术后出现鼻漏(术后第7天和第30天)——14.2%。没有脑膜炎迹象,也没有死亡病例。未观察到视力障碍和鞍区填充过度的情况。
在鞍区重建手术中使用速即纱可降低术后脑脊液漏的风险,并消除鞍区填充过度和视力恶化的特征。