Persistent coronavirus infection of progenitor oligodendrocytes.
作者信息
Liu Yin, Zhang Xuming
机构信息
University of Arkansas for Medical Sciences, Little Rock 72205, USA.
出版信息
Adv Exp Med Biol. 2006;581:379-84. doi: 10.1007/978-0-387-33012-9_67.
Abstract
摘要
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Expression of cellular oncogene Bcl-xL prevents coronavirus-induced cell death and converts acute infection to persistent infection in progenitor rat oligodendrocytes.
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Induction of caspase-dependent apoptosis in cultured rat oligodendrocytes by murine coronavirus is mediated during cell entry and does not require virus replication.
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