Williams Joanne, Wasserberger Jonathan
Department of Emergency Medicine, Martin Luther King, Jr./Charles R. Drew Medical Center, Charles R. Drew University of Medicine and Science, Los Angeles, California, USA.
J Emerg Med. 2006 Aug;31(2):181-4. doi: 10.1016/j.jemermed.2005.08.021.
Cocaine is the most powerful central nervous stimulant found in nature. All forms of cocaine cause tachycardia and vasoconstriction. A smokable, rapidly reacting form of cocaine base, "crack," is highly addictive. Smoking crack introduces a high concentration of cocaine into the bloodstream, rendering it especially dangerous. We report a case that visually demonstrates severe aortic vasoconstriction from the suprarenal aorta and extending to both femoral arteries and beyond, resulting in renal failure and fatal bowel ischemia after a 5-day binge of crack cocaine.
可卡因是自然界中发现的最强大的中枢神经兴奋剂。所有形式的可卡因都会导致心动过速和血管收缩。一种可吸食的、反应迅速的可卡因碱形式“快克”极易上瘾。吸食快克会使高浓度的可卡因进入血液,使其特别危险。我们报告了一例病例,直观地显示了从肾上腺主动脉到双侧股动脉及更远部位的严重主动脉血管收缩,导致在连续5天吸食快克后出现肾衰竭和致命的肠缺血。