Berlin Alexander, Cohen Joel L, Goldberg David J
Mount Sinai School of Medicine, New York, NY, USA.
Semin Cutan Med Surg. 2006 Sep;25(3):132-7. doi: 10.1016/j.sder.2006.06.005.
Porous calcium hydroxylapatite has been used in otolaryngology, dentistry and radiology for many years. Currently, calcium hydroxylapatite is gaining popularity for facial esthetics in the form of the product Radiesse (San Mateo, CA). Although Radiesse is not yet approved in the United States for cosmetic use, it is being used off-label by an increasing number of dermatologists and plastic surgeons for facial soft-tissue augmentation. Preliminary clinical and histologic studies have shown safety, efficacy and durability in various esthetic applications including the nasolabial folds and HIV lipoatrophy.
多孔羟基磷灰石已在耳鼻喉科、牙科和放射学领域使用多年。目前,羟基磷灰石以瑞蓝(Radiesse,加利福尼亚州圣马特奥)产品的形式在面部美容方面越来越受欢迎。尽管瑞蓝在美国尚未被批准用于美容用途,但越来越多的皮肤科医生和整形外科医生正在超适应症使用它来进行面部软组织填充。初步的临床和组织学研究表明,在包括鼻唇沟和HIV脂肪萎缩在内的各种美容应用中,它具有安全性、有效性和持久性。