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孤立性结膜溃疡作为白塞病的首发症状

Isolated conjunctival ulcerations as the first sign of Behçet's disease.

作者信息

Merle H, Donnio A, Richer R, Dubreuil F, Arfi S

机构信息

Service d'Ophtalmologie, Centre Hospitalier Universitaire de Fort de France, Hôpital Pierre Zobda-Quitman, Martinique, France (French West Indies).

出版信息

Eur J Ophthalmol. 2006 Sep-Oct;16(5):751-2.

Abstract

PURPOSE

To report an unusual incident of isolated conjunctival ulcerations which preceded all other signs of Behçet's disease.

METHODS

Description of a 34-year-old woman of West Indian origin with an unremarkable medical history presenting with bilateral bulbar conjunctival ulcerations.

RESULTS

The authors noted the presence of a diffuse bilateral conjunctival hyperemia which was more pronounced at the temporal bulbar conjunctiva of the right eye and the nasal conjunctiva of the left eye, each having one ulceration. The rest of the ophthalmologic examination was normal. One month later, the appearance of buccogenital aphthosis led to the diagnosis of Behçet's disease.

CONCLUSIONS

This observation is unusual, as the conjunctival ulcerations are isolated and precede the onset of all other symptoms of Behçet's disease. Conjunctival ulcerations are rarely seen with Behçet's disease, but are characteristic enough to be included among the diagnostic criteria.

摘要

目的

报告一例白塞病所有其他症状出现之前孤立性结膜溃疡的罕见病例。

方法

描述一名34岁西印度裔女性,既往病史无异常,出现双侧球结膜溃疡。

结果

作者注意到存在弥漫性双侧结膜充血,右眼颞侧球结膜和左眼鼻侧结膜更为明显,各有一处溃疡。其余眼科检查正常。一个月后,出现口腔生殖器溃疡,从而诊断为白塞病。

结论

该病例不常见,因为结膜溃疡是孤立性的,且先于白塞病所有其他症状出现。白塞病很少见结膜溃疡,但具有足够的特征性,可纳入诊断标准。

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