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新生儿社区获得性耐甲氧西林金黄色葡萄球菌坏死性筋膜炎

Community-associated methicillin-resistant Staphylococcus aureus necrotizing fasciitis in a neonate.

作者信息

Dehority Walter, Wang Emily, Vernon Patty S, Lee Carla, Perdreau-Remington Francoise, Bradley John

机构信息

University of California, San Diego School of Medicine, CA, USA.

出版信息

Pediatr Infect Dis J. 2006 Nov;25(11):1080-1. doi: 10.1097/01.inf.0000243158.25713.29.

Abstract

Neonatal necrotizing fasciitis is rare and is predominantly associated with methicillin-susceptible Staphylococcus aureus (MSSA). Necrotizing fasciitis associated with community-associated methicillin-resistant S aureus (CA-MRSA) has only recently been reported in the literature, primarily among adults. We present a case of a previously healthy neonate with necrotizing fasciitis of the back caused by CA-MRSA, pulsed-field type USA-300. We describe a 5-day-old infant with necrotizing fasciitis of the back caused by CA-MRSA. Treatment of necrotizing fasciitis requires prompt medical evaluation, prompt surgical debridement, and appropriate antibiotic selection. The potential involvement of CA-MRSA in necrotizing fasciitis in children needs to be considered before institution of antibiotics.

摘要

新生儿坏死性筋膜炎较为罕见,主要与对甲氧西林敏感的金黄色葡萄球菌(MSSA)相关。与社区获得性耐甲氧西林金黄色葡萄球菌(CA-MRSA)相关的坏死性筋膜炎最近才在文献中有所报道,主要发生在成年人中。我们报告一例既往健康的新生儿,患有由CA-MRSA(脉冲场型USA-300)引起的背部坏死性筋膜炎。我们描述了一名5天大的婴儿,患有由CA-MRSA引起的背部坏死性筋膜炎。坏死性筋膜炎的治疗需要及时进行医学评估、及时进行外科清创以及选择合适的抗生素。在使用抗生素之前,需要考虑CA-MRSA在儿童坏死性筋膜炎中的潜在作用。

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