Batoni G, Maisetta G, Esin S, Campa M
Dipartimento di Patologia sperimentale, Biotecnologie mediche, Infettivologia ed Epidemiologia, Via S. Zeno 35-39, University of Pisa, 56127 Pisa, Italy.
Mini Rev Med Chem. 2006 Oct;6(10):1063-73. doi: 10.2174/138955706778560193.
The field of naturally occurring antimicrobial peptides is a research area rapidly expanding due to the high potential of such molecules as new antimicrobial drugs. In this regard, the human beta-defensin-3 is particularly attractive because of its strong antibacterial activity, relative salt-insensitiveness and low toxicity for host cells.
由于天然存在的抗菌肽作为新型抗菌药物具有很高的潜力,该领域是一个正在迅速扩展的研究领域。在这方面,人β-防御素-3因其强大的抗菌活性、相对的盐不敏感性以及对宿主细胞的低毒性而特别具有吸引力。