Kessler Thomas M, Burkhard Fiona C, Studer Urs E
Department of Urology, University of Bern, Bern, Switzerland.
Eur Urol. 2007 Jan;51(1):90-7. doi: 10.1016/j.eururo.2006.10.013. Epub 2006 Oct 23.
In recent years, the surgical technique for open radical prostatectomy has evolved and increasing attention is paid to preserving anatomic structures and the impact on outcome and quality of life.
Technical aspects of nerve-sparing open radical retropubic prostatectomy (RRP) are described. Patient selection criteria and functional results are discussed, focusing on postoperative urinary continence.
The video demonstrates the nerve-sparing open RRP and important steps are elucidated with schematic drawings. The value of nerve sparing, not only for preserving erectile function, but also for preserving urinary continence is discussed and results from our institution are presented. In our series, urinary incontinence was present in 1 of 71 patients (1%) with attempted bilateral nerve-sparing, 11 of 322 (3%) with attempted unilateral nerve-sparing, or 19 of 139 (14%) without attempted nerve-sparing surgery. In multiple logistic regression analysis, the only statistically significant factor influencing urinary continence after open RRP was attempted nerve sparing (odds ratio, 4.77; 95% confidence interval, 2.18-10.44; p=0.0001).
Nerve-sparing surgery has a significant impact on erectile function and urinary continence and should be performed in all patients provided radical tumour resection is not compromised. For successful nerve preservation we advocate a lateral approach to the prostate to improve visualisation and simplify separation of the neurovascular bundles from the dorsolateral prostatic capsule. Bunching, ligating, and incising Santorini's plexus over the prostate and not over the sphincter ensures a bloodless surgical field. Mucosa-to-mucosa adaptation of the reconstructed bladder neck and the urethra is another important factor to be observed.
近年来,开放性根治性前列腺切除术的手术技术不断发展,人们越来越关注保留解剖结构以及对手术结果和生活质量的影响。
描述了保留神经的开放性耻骨后根治性前列腺切除术(RRP)的技术要点。讨论了患者选择标准和功能结果,重点是术后尿失禁情况。
视频展示了保留神经的开放性RRP,并通过示意图阐明了重要步骤。讨论了保留神经的价值,不仅在于保留勃起功能,还在于保留尿失禁功能,并展示了我们机构的结果。在我们的系列研究中,71例尝试双侧保留神经的患者中有1例(1%)出现尿失禁,322例尝试单侧保留神经的患者中有11例(3%)出现尿失禁,139例未尝试保留神经手术的患者中有19例(14%)出现尿失禁。在多因素逻辑回归分析中,影响开放性RRP术后尿失禁的唯一具有统计学意义的因素是尝试保留神经(优势比,4.77;95%置信区间,2.18 - 10.44;p = 0.0001)。
保留神经手术对勃起功能和尿失禁有显著影响,在不影响根治性肿瘤切除的情况下,所有患者均应进行该手术。为了成功保留神经,我们提倡采用前列腺外侧入路,以改善视野并简化神经血管束与前列腺背外侧包膜的分离。在前列腺而非括约肌上方束扎、结扎和切开Santorini丛可确保手术视野无血。重建膀胱颈和尿道的黏膜对黏膜吻合是另一个需要注意的重要因素。