Hudson Lynsee A, Bernard Timothy J, Tseng Brian S, Miller Bradford R, Corboy John R
Department of Neurology, University of Colorado at Denver and Health Sciences Center, Denver, CO 80262, USA.
Pediatr Neurol. 2006 Nov;35(5):370-2. doi: 10.1016/j.pediatrneurol.2006.06.008.
Neuromyelitis optica or Devic's syndrome is an uncommon demyelinating disorder that preferentially attacks the spinal cord and optic nerves. Although it is well described in adults, childhood neuromyelitis optica has rarely been reported in the literature and is frequently misdiagnosed as severe multiple sclerosis. Recently, a serum immunoglobulin G test for neuromyelitis optica has become available which may clarify and accelerate the diagnosis. This report describes a child with recurrent myelitis and an elongated spinal cord lesion who was found to have positive neuromyelitis optica autoantibody. We believe that neuromyelitis optica autoantibody testing should be performed in cases of pediatric transverse myelitis with multiple vertical segments or recurrence.
视神经脊髓炎或德维克综合征是一种罕见的脱髓鞘疾病,主要侵袭脊髓和视神经。虽然在成人中已有详细描述,但儿童视神经脊髓炎在文献中鲜有报道,且常被误诊为重症多发性硬化症。最近,一种针对视神经脊髓炎的血清免疫球蛋白G检测已可进行,这可能会使诊断更加明确并加快诊断速度。本报告描述了一名患有复发性脊髓炎和脊髓长病变的儿童,该儿童被发现视神经脊髓炎自身抗体呈阳性。我们认为,对于患有多个垂直节段或复发性小儿横贯性脊髓炎的病例,应进行视神经脊髓炎自身抗体检测。