Horowitz Barbara Natterson, Vaseghi Marmar, Mahajan Aman, Cesario David A, Buch Eric, Valderrábano Miguel, Boyle Noel G, Ellenbogen Kenneth A, Shivkumar Kalyanam
UCLA Cardiac Arrhythmia Center, Division of Cardiology, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California 90095, USA.
Heart Rhythm. 2006 Nov;3(11):1275-82. doi: 10.1016/j.hrthm.2006.07.025. Epub 2006 Aug 3.
Percutaneous pericardial access, epicardial mapping, and ablation have been used successfully for catheter ablation procedures.
The purpose of this study was to evaluate the safety and feasibility of closed-chest direct epicardial ultrasound imaging for aiding cardiac catheter ablation procedures.
An intracardiac ultrasound catheter was used for closed-chest epicardial imaging of the heart in 10 patients undergoing percutaneous epicardial access for catheter ablation. All patients underwent concomitant intracardiac echocardiography and preprocedural transesophageal echocardiography. Using a double-wire technique, two sheaths were placed in the pericardium, and a phased-array ultrasound catheter was manipulated within the pericardial sinuses for imaging.
Multiple images from varying angles were obtained for catheter navigation. Notably, image stability was excellent, and structures such as the left atrial appendage were seen in great detail. No complications resulting from use of the ultrasound catheter in the pericardium occurred, and no restriction of movement due to the presence of the additional catheter in the pericardial space was observed. Wall motion was correlated to voltage maps in five patients and showed that areas of scars correlated with wall-motion abnormalities. Normal wall-motion score correlated to sensed signals of 4.2 +/- 0.3 mV (normal myocardium >1.5 mV), and scores >1 correlated to areas with signals <0.5 mV in that territory).
Intrapericardial imaging using an ultrasound catheter is feasible and safe and has the potential to provide additional valuable information for complex ablation procedures.
经皮心包穿刺、心外膜标测及消融已成功应用于导管消融手术。
本研究旨在评估闭式胸腔直接心外膜超声成像辅助心脏导管消融手术的安全性和可行性。
在10例接受经皮心外膜穿刺导管消融的患者中,使用心腔内超声导管进行闭式胸腔心外膜心脏成像。所有患者均同时接受心腔内超声心动图检查及术前经食管超声心动图检查。采用双线技术,在心包内放置两个鞘管,并在心包窦内操纵相控阵超声导管进行成像。
获取了不同角度的多幅图像用于导管导航。值得注意的是,图像稳定性极佳,左心耳等结构清晰可见。未发生因在心包内使用超声导管导致的并发症,也未观察到因心包腔内额外导管的存在而限制活动。5例患者的室壁运动与电压图相关,显示瘢痕区域与室壁运动异常相关。正常室壁运动评分与感知信号4.2±0.3 mV相关(正常心肌>1.5 mV),评分>1与该区域信号<0.5 mV的区域相关。
使用超声导管进行心包内成像可行且安全,有可能为复杂消融手术提供额外有价值的信息。