Palo Riikka, Capraro Leena, Hovilehto Seppo, Koivuranta Merja, Krusius Tom, Loponen Elina, Mäntykoski Ritva, Pentti Jussi, Pitkänen Otto, Raitakari Maria, Rimpiläinen Jussi, Salmenperä Markku, Salo Hanna, Mäki Tiina
Finnish Red Cross Blood Service, Helsinki, Finland.
Transfusion. 2006 Nov;46(11):1921-5. doi: 10.1111/j.1537-2995.2006.00998.x.
In contrast to decreasing red blood cell (RBC) consumption in Finland, the use of fresh-frozen plasma (FFP) has been increasing since the 1990s, suggesting that FFP use may not always be optimal. To improve transfusion practices, knowledge of current FFP use and regional, national, and international comparison is necessary.
Nine (of 21) Finnish hospital districts participated. Data concerning FFP-transfused patients in the years 2002 and 2003 were collected from existing computerized medical records into a yearly updated database as part of a Finnish benchmarking project on blood component use.
Data included 11,590 FFP-transfused patients and 60,240 FFP units (71.2% of Finnish FFP use) delivered to Finnish hospitals during the study period. FFP was transfused most often to surgery patients (62.8% of FFP transfusion hospital visits) with blood circulatory system problems (32.3% of surgically treated and FFP-transfused patients). In only 65.9 percent of FFP-transfused patients were coagulation variables measured at any point in the hospital episode, and FFP was usually transfused in paired doses. Mean FFP use in Finland is comparable to other countries.
Although overall FFP use in Finland is similar to that of international figures, it does not ensure best practice. Perioperative staff, being the largest FFP user, should be encouraged to dose FFP based on coagulation variables and body weight. Improvement efforts should be directed to patient groups transfused with large amounts of FFP.
与芬兰红细胞（RBC）消耗量下降形成对比的是，自20世纪90年代以来新鲜冰冻血浆（FFP）的使用一直在增加，这表明FFP的使用可能并非总是最佳的。为了改善输血实践，了解当前FFP的使用情况以及地区、国家和国际间的比较是必要的。
芬兰21个医院区中的9个参与了研究。作为芬兰血液成分使用基准项目的一部分，2002年和2003年FFP输血患者的数据从现有的计算机化医疗记录中收集到一个年度更新的数据库中。
数据包括研究期间输送到芬兰医院的11,590例FFP输血患者和60,240单位FFP（占芬兰FFP使用量的71.2%）。FFP最常输给有血液循环系统问题的手术患者（占FFP输血医院就诊病例的62.8%）（占接受手术治疗并输注FFP患者的32.3%）。在仅65.9%的FFP输血患者中，在住院期间的任何时间点测量了凝血变量，并且FFP通常以配对剂量输注。芬兰FFP的平均使用量与其他国家相当。
尽管芬兰FFP的总体使用情况与国际数据相似，但这并不能确保最佳实践。作为最大的FFP使用者，围手术期工作人员应被鼓励根据凝血变量和体重来确定FFP的剂量。改进工作应针对输注大量FFP的患者群体。
