脑膜瘤的新型治疗方法。
Novel therapies for meningiomas.
作者信息
Wen Patrick Y, Drappatz Jan
机构信息
Center for Neuro-Oncology Dana-Farber/Brigham and Women's Cancer Center, and Division of Neuro-Oncology, Department of Neurology, Brigham and Women's Hospital, Boston, MA 02115, USA.
出版信息
Expert Rev Neurother. 2006 Oct;6(10):1447-64. doi: 10.1586/14737175.6.10.1447.
Although advances in surgery, radiation therapy and stereotactic radiosurgery have significantly improved the treatment of meningiomas, there remains an important subset of patients who remain refractory to conventional therapy. Treatment with chemotherapeutic agents such as hydroxyurea and alpha-interferon has provided minimal benefit. In this review, the role of newly emerging novel therapies for meningiomas, with a focus on targeted molecular agents, will be discussed.
尽管手术、放射治疗和立体定向放射外科取得了进展，显著改善了脑膜瘤的治疗效果，但仍有一部分重要患者对传统治疗方法难治。使用羟基脲和α-干扰素等化疗药物进行治疗的获益甚微。在本综述中，将讨论新兴的脑膜瘤新型疗法的作用，重点是靶向分子药物。
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