Miao Huadong, Fukatsu Hiroshi, Ishigaki Takeo
Department of Radiology, Nagoya University Graduate School of Medicine, 65 Tsurumai, Nagoya 4668550, Japan.
Eur J Radiol. 2007 Feb;61(2):297-302. doi: 10.1016/j.ejrad.2006.10.002. Epub 2006 Nov 7.
To compare the clinical value of diffusion-weighted (DW) and T2-weighted (T2W) imaging in detecting prostate cancer using a 3-Tesla (3T) magnetic resonance (MR) system.
Thirty-seven patients with suspected prostate cancer underwent T2W and DW imaging at 3T using an 8-channel phased-array coil. These images and apparent diffusion coefficient (ADC) maps were read retrospectively and blindly. The results were compared with histopathologic findings, and receiver operating characteristic (ROC) analysis was used to compare the cancer detection performance of T2W and DW imaging.
The areas under the ROC curves for DW imaging and T2W imaging were 0.89 and 0.82, respectively. The performance of DW imaging in prostate cancer detection was significantly better than that of T2W imaging (P=0.0371).
With a 3T MR system, the performance of DW imaging in detecting prostate cancer was better than that of T2W imaging. DW imaging appears to be a robust and reliable method to examine the whole prostate within an acceptable scan time in clinical settings.
使用3特斯拉（3T）磁共振（MR）系统比较扩散加权（DW）成像和T2加权（T2W）成像在检测前列腺癌中的临床价值。
37例疑似前列腺癌患者使用8通道相控阵线圈在3T下进行T2W和DW成像。对这些图像和表观扩散系数（ADC）图进行回顾性盲法阅读。将结果与组织病理学结果进行比较，并使用受试者操作特征（ROC）分析来比较T2W和DW成像的癌症检测性能。
DW成像和T2W成像的ROC曲线下面积分别为0.89和0.82。DW成像在前列腺癌检测中的性能明显优于T2W成像（P = 0.0371）。
对于3T MR系统，DW成像在检测前列腺癌方面的性能优于T2W成像。在临床环境中，DW成像似乎是一种在可接受的扫描时间内检查整个前列腺的强大且可靠的方法。
