Baumann I, Harms H, Kuse R, Feller A C, Müller-Hermelink H K
Pathologisches Institut, Universität Würzburg.
Verh Dtsch Ges Pathol. 1990;74:135-8.
Blast-cells in Romanowsky-Giemsa stained bone marrow smears from 14 cases of primary myelodysplastic syndrome which consequently developed an acute myeloid leukemia and 28 cases of primary acute myeloid leukemia were analysed by a computer aided high resolution pattern recognition system. As control we used blast-cells from reactive affected bone marrow. Whereas blast-cell types in MDS and secondary AML showed overlapping features and a heterogenous distribution we could distinguish blasts in primary AML compared to "reactive" blasts. Opposite to this blasts in secondary AML showed no different pattern compared to "reactive" blast.
运用计算机辅助高分辨率模式识别系统，对14例最终发展为急性髓系白血病的原发性骨髓增生异常综合征患者以及28例原发性急性髓系白血病患者的罗曼诺夫斯基-吉姆萨染色骨髓涂片上的原始细胞进行了分析。作为对照，我们使用了反应性受累骨髓中的原始细胞。虽然骨髓增生异常综合征和继发性急性髓系白血病中的原始细胞类型表现出重叠特征和异质性分布，但与“反应性”原始细胞相比，我们能够区分原发性急性髓系白血病中的原始细胞。与此相反，继发性急性髓系白血病中的原始细胞与“反应性”原始细胞相比，没有显示出不同的模式。
