Schiavano G F, Sisti M, De Santi M, Brandi G
Istituto di Scienze Tossicologiche Igienistiche ed Ambientali, Università degli Studi di Urbino "Carlo Bo".
Ann Ig. 2006 Sep-Oct;18(5):375-82.
Peracetic acid (PAA) is a disinfectant with a wide spectrum of antimicrobial activity, but little is known about the feasibility of using it in the field of drinking water treatment. The aim of this study has been assess disinfectant efficacy of PAA, alone or in combination with hypochlorite, against M. avium in drinking water M. avium is a common opportunistic pathogen in immunocompromised subjects that is able to survive and grow in drinking water distribution systems. In this study PAA did not show appreciable activity against the greater number of tested strains (16/21) up to 5 ppm of PAA, a weak activity was seen on 4 strains, while a significant reduction in viable cells (about 50%) was seen only on 1 strain after 48 h of treatment with 5 ppm of PAA. We also evidenced that M. avium was unaffected by chlorine concentration usually present in drinking water distribution system. Finally, the combination of PAA and sodium hypochlorite did not promote enhanced antimicrobial efficacy respect to the single disinfectants. In conclusion, our result would indicate that PAA is an unlikely candidate for the disinfection of drinking water from M. avium and further strategies are required to eliminate M. avium from drinking water system.
过氧乙酸（PAA）是一种具有广泛抗菌活性的消毒剂，但对于其在饮用水处理领域应用的可行性了解甚少。本研究的目的是评估PAA单独使用或与次氯酸盐联合使用时，对饮用水中鸟分枝杆菌的消毒效果。鸟分枝杆菌是免疫功能低下者中常见的机会性病原体，能够在饮用水分配系统中存活和生长。在本研究中，高达5 ppm的PAA对大多数测试菌株（16/21）未显示出明显活性，对4株菌株显示出较弱活性，而在用5 ppm的PAA处理48小时后，仅对1株菌株观察到活菌数显著减少（约50%）。我们还证明，饮用水分配系统中通常存在的氯浓度对鸟分枝杆菌没有影响。最后，PAA和次氯酸钠的组合相对于单一消毒剂并未提高抗菌效果。总之，我们的结果表明，PAA不太可能用于饮用水中鸟分枝杆菌的消毒，需要进一步采取策略从饮用水系统中消除鸟分枝杆菌。
