Wenzel S, Mollenhauer B, Trenkwalder C
Paracelsus-Elena-Klinik, Klinikstrasse 16, 34128 Kassel, Germany.
Nervenarzt. 2006 Dec;77(12):1439-43. doi: 10.1007/s00115-006-2179-7.
For decades, awareness of Parkinson's disease mainly focused on the presence and treatment of motor symptoms. More and more other symptoms of this disease not related to the motor system now receive increased attention, including cognitive decline. Dementia in Parkinson's disease occurs more often than initially was thought. After an average of 8 years, about 40% of these patients suffer from cognitive decline. The difficulties and related problems affect prognosis more than do the motor symptoms. There is a need for standardized diagnostic and specific therapeutic intervention, but appropriate studies are still lacking.
几十年来,帕金森病的认知主要集中在运动症状的存在与治疗上。现在,这种疾病越来越多与运动系统无关的其他症状受到更多关注,包括认知衰退。帕金森病中的痴呆比最初认为的更为常见。平均8年后,约40%的这些患者会出现认知衰退。这些困难及相关问题对预后的影响比运动症状更大。需要标准化诊断和特定的治疗干预,但仍缺乏适当的研究。