Citro Rodolfo, Galderisi Maurizio, Maione Antongiulio, Innelli Pasquale, Provenza Gennaro, Gregorio Giovanni
Department of Cardiology, San Luca Hospital, Vallo della Lucania, Salerno, Italy.
J Am Soc Echocardiogr. 2006 Nov;19(11):1402.e5-8. doi: 10.1016/j.echo.2006.07.014.
We report a case of a 70-year-old woman with Tako-tsubo syndrome admitted to the hospital with typical chest pain and electrocardiogram changes in anterior precordial leads suggesting acute coronary syndrome. Coronary angiography demonstrated normal coronary artery and left ventriculography the typical apical ballooning of Tako-tsubo syndrome. Transthoracic echocardiographically derived coronary flow velocity reserve by adenosine was lower than normal (1.54) in the acute phase and improved after 1 month (2.68). At this time, electrocardiogram normalization also occurred. Our report supports the hypothesis that coronary microvascular dysfunction might be a determinant of Tako-tsubo syndrome.
我们报告一例70岁女性的应激性心肌病病例，该患者因典型胸痛及胸前导联心电图改变提示急性冠脉综合征而入院。冠状动脉造影显示冠状动脉正常，左心室造影显示应激性心肌病典型的心尖部气球样变。经胸超声心动图检测，急性期通过腺苷测得的冠状动脉血流储备低于正常水平（1.54），1个月后有所改善（2.68）。此时，心电图也恢复正常。我们的报告支持冠状动脉微血管功能障碍可能是应激性心肌病决定因素这一假说。
