Leung Cheung, Chang Yi-Chen
Division of Neonatology, Department of Pediatrics, Far Eastern Memorial Hospital, Panchiao, Taipei, Taiwan.
J Formos Med Assoc. 2006 Nov;105(11):936-40. doi: 10.1016/S0929-6646(09)60179-0.
Pleural empyema is a frequent complication of bacterial pneumonia in childhood but is rare in neonates. Various modalities of treatment from intravenous antibiotics, chest tube drainage, intrapleural fibrinolytic agent installation, video-assisted thoracostomy to surgical decortication have been suggested to treat different stages of empyema in children, but management of progressive empyema in neonates is still at the stage of antimicrobial therapy and tube thoracostomy. Here, we report a 1-month-old infant with staphylococcal pneumonia complicated with multiloculated empyema who was successfully treated with video-assisted thoracoscopic surgery (VATS) after 4 days of chest tube drainage and parenteral antibiotics. The patient's condition improved rapidly after the operation and the antimicrobial therapy was continued for 3 weeks. He was asymptomatic and thriving at follow-up 1 year later. Chest radiography at 1 month was free of any lesion. This case suggests that VATS can be a safe and effective treatment for neonatal empyema.
脓胸是儿童细菌性肺炎的常见并发症,但在新生儿中很少见。对于儿童脓胸的不同阶段,已提出了多种治疗方法,从静脉使用抗生素、胸腔闭式引流、胸腔内注入纤维蛋白溶解剂、电视辅助胸腔镜手术到外科胸膜剥脱术,但新生儿进行性脓胸的治疗仍处于抗菌治疗和胸腔闭式引流阶段。在此,我们报告一名1个月大的婴儿,患有金黄色葡萄球菌肺炎合并多房性脓胸,在胸腔闭式引流和静脉使用抗生素4天后,通过电视辅助胸腔镜手术(VATS)成功治愈。术后患者病情迅速改善,并继续抗菌治疗3周。1年后随访时,他无症状且生长发育良好。1个月时的胸部X线检查未发现任何病变。该病例表明,VATS对于新生儿脓胸可能是一种安全有效的治疗方法。