绝经前异常子宫出血女性的子宫内膜厚度筛查
Endometrial thickness screening in premenopausal women with abnormal uterine bleeding.
作者信息
Getpook Chatpavit, Wattanakumtornkul Saranya
机构信息
Division of Reproductive Medicine, Department of Obstetrics and Gynecology, Faculty of Medicine, Prince of Songkhla University, Songkhla, Thailand.
出版信息
J Obstet Gynaecol Res. 2006 Dec;32(6):588-92. doi: 10.1111/j.1447-0756.2006.00455.x.
AIM
To assess the role of measuring endometrial thickness by transvaginal ultrasonography (TVS) as a screening tool for abnormal uterine bleeding triage in premenopausal women.
METHODS
Between November 2002 and October 2004, endometrial thickness was measured by TVS in 111 premenopausal women with non-cyclic abnormal uterine bleeding before dilatation and curettage.
RESULTS
Of the 111 women, 31 (27.9%) had an abnormal endometrium (hyperplasia 13.5%, polyps 5.4%, submucous myoma 5.4%, and adenocarcinoma 3.6%). An endometrial thickness of 8 mm showed optimal sensitivity and specificity (83.9% and 58.8%, respectively) and 90.4% negative predictive value (NPV) for an abnormal endometrium. When submucous myoma was excluded, the sensitivity, specificity, and NPV were 80%, 53.8%, and 89.6%, respectively.
CONCLUSION
Endometrial thickness of 8 mm or less is less likely to be associated with malignant pathologies in premenopausal uterine bleeding.
目的
评估经阴道超声检查（TVS）测量子宫内膜厚度作为绝经前女性异常子宫出血分诊筛查工具的作用。
方法
2002年11月至2004年10月期间，对111例绝经前非周期性异常子宫出血的女性在刮宫术前进行经阴道超声检查测量子宫内膜厚度。
结果
111例女性中，31例（27.9%）子宫内膜异常（增生13.5%，息肉5.4%，黏膜下肌瘤5.4%，腺癌3.6%）。子宫内膜厚度为8mm时，对异常子宫内膜显示出最佳的敏感性和特异性（分别为83.9%和58.8%）以及90.4%的阴性预测值（NPV）。排除黏膜下肌瘤后，敏感性、特异性和NPV分别为80%、53.8%和89.6%。
结论
绝经前子宫出血中，子宫内膜厚度小于或等于8mm与恶性病变相关的可能性较小。
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