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重组组织型纤溶酶原激活剂(r-TPA)在术后眼内炎所致纤维蛋白溶解中的作用

Recombinant tissue plasminogen activator (r-TPA) in fibrin dissolution due to postoperative endophthalmitis.

作者信息

Riaz Yasmin, Mehta Jodhbir S, Fernando Arosho, Ferguson Veronica

机构信息

The Western Eye Hospital, Marylebone Road, London, UK.

出版信息

Ann Acad Med Singap. 2006 Oct;35(10):723-5.

Abstract

INTRODUCTION

The aim of this paper was to describe the use of r-TPA for fibrin clot dissolution following endophthalmitis.

CLINICAL PICTURE

A 74-year-old man presented with painful loss of vision following routine uncomplicated cataract surgery.

TREATMENT

He underwent standard treatment for postoperative endophthalmitis but despite this, developed a dense fibrin clot. He underwent further intracameral injection of r-TPA.

OUTCOME

Following the injection, he had complete clot dissolution within 2 hours without any complications.

CONCLUSION

R-TPA may be used effectively in the treatment of fibrin clots secondary to endophthalmitis following cataract surgery.

摘要

引言

本文旨在描述重组组织型纤溶酶原激活剂(r-TPA)在眼内炎后溶解纤维蛋白凝块中的应用。

临床情况

一名74岁男性在常规无并发症白内障手术后出现视力疼痛性丧失。

治疗

他接受了术后眼内炎的标准治疗,但尽管如此,仍形成了致密的纤维蛋白凝块。他接受了进一步的前房内注射r-TPA。

结果

注射后,他在2小时内凝块完全溶解,无任何并发症。

结论

r-TPA可有效用于治疗白内障手术后眼内炎继发的纤维蛋白凝块。

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