Tallur P N, Megadi V B, Kamanavalli C M, Ninnekar H Z
Department of Biochemistry, Karnataka University, Dharwad, 580003, India.
Curr Microbiol. 2006 Dec;53(6):529-33. doi: 10.1007/s00284-006-0309-x. Epub 2006 Nov 13.
A bacterium capable of utilizing p-cresol as sole source of carbon and energy was isolated from soil and identified as a Bacillus species. The organism also utilized phenol, o-cresol, m-cresol, 4-hydroxybenzoic acid, and gentisic acid as growth substrates. The organism degraded p-cresol to 4-hydroxybenzoic acid, which was further metabolized by a gentisate pathway, as evidenced by isolation and identification of metabolites and enzyme activities in the cell-free extract. Such a bacterial strain can be used for bioremediation of environments contaminated with phenolic compounds.
从土壤中分离出一种能够利用对甲酚作为唯一碳源和能源的细菌,并鉴定为芽孢杆菌属。该微生物还利用苯酚、邻甲酚、间甲酚、4-羟基苯甲酸和龙胆酸作为生长底物。该微生物将对甲酚降解为4-羟基苯甲酸,4-羟基苯甲酸再通过龙胆酸途径进一步代谢,这一点可通过在无细胞提取物中分离和鉴定代谢产物及酶活性得到证明。这样的细菌菌株可用于对受酚类化合物污染的环境进行生物修复。