Okmen Arda Sanli
Int J Cardiol. 2007 Sep 14;121(1):97-9. doi: 10.1016/j.ijcard.2006.08.038. Epub 2006 Nov 13.
Coronary artery aneurysm is defined as coronary dilatation, which exceeds the diameter of normal adjacent segment or the diameter of the patient's largest coronary vessel by 1.5 times [Syed M, Lesch M: Coronary artery aneurysms: a review. Prog Cardiovasc Dis 1997; 40:77-10 84 [1]]. Most studies show an incidence of 1% to 2% [Barettella MB, Bott-Silverman C. Coronary artery aneurysm: an unusual case report and a review of the literature. Cathet Cardiovasc Diagn 1993; 29:57-61 [2]]. Left main coronary aneurysms (LMCA) are even more rare; in a study by involving 22,000 coronary angiograms an occurrence rate of 0.1% has been found [Topaz O, DiSciascio G, Cowley MJ, Goudreau E, Soffer A, Nath A et al. Angiographic features of left main coronary artery aneurysms. Am J Cardiol 1991; 67:1139-1142 [3]]. The majority of patients present with ischemic symptoms secondary to the coexisting atherosclerotic lesions and most of the coronary aneurysms are incidentally diagnosed by coronary angiography. This report details the exceptional case of a 62-year-old patient with "unusually long fusiform" aneurysm of the left main coronary artery associated with critical left main coronary artery distal stenosis involving the ostia of left anterior descending and left circumflex coronary artery. With this case the possible anatomic determinants of the type, location, and mechanism of aneurysm formation were also discussed.
冠状动脉瘤被定义为冠状动脉扩张,其直径超过相邻正常节段的直径或患者最大冠状动脉直径的1.5倍[Syed M, Lesch M:冠状动脉瘤:综述。心血管疾病进展1997;40:77 - 10 84 [1]]。大多数研究显示发病率为1%至2%[Barettella MB, Bott - Silverman C.冠状动脉瘤:一例罕见病例报告及文献复习。心血管造影诊断1993;29:57 - 61 [2]]。左主干冠状动脉瘤(LMCA)更为罕见;在一项涉及22000例冠状动脉造影的研究中,发现其发生率为0.1%[Topaz O, DiSciascio G, Cowley MJ, Goudreau E, Soffer A, Nath A等。左主干冠状动脉瘤的血管造影特征。美国心脏病学杂志1991;67:1139 - 1142 [3]]。大多数患者表现为继发于并存动脉粥样硬化病变的缺血症状,大多数冠状动脉瘤是通过冠状动脉造影偶然诊断出来的。本报告详细介绍了一例62岁患者的特殊病例,该患者左主干冠状动脉存在“异常长的梭形”动脉瘤,并伴有左主干冠状动脉远端严重狭窄,累及左前降支和左旋支冠状动脉开口。结合该病例,还讨论了动脉瘤形成类型、位置和机制的可能解剖学决定因素。