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Mutations leading to loss of sporulation ability in Bacillus subtilis are sufficiently frequent to favor genetic canalization.

作者信息

Masel Joanna, Maughan Heather

机构信息

Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, Arizona 85721, USA.

出版信息

Genetics. 2007 Jan;175(1):453-7. doi: 10.1534/genetics.106.065201. Epub 2006 Nov 16.

Abstract

We measured the rate of mutations impairing sporulation ability in Bacillus subtilis as 0.003 in a mutator population, following 6000 generations of strong selection for sporulation that have previously been described. This means that the product of the population size and the functional mutation rate is approximately 10(5), well within the parameter range for which genetic canalization of sporulation ability is expected.

摘要

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