Sánchez-Margallo F M, Loscertales B, Díaz-Güemes I, Usón J
Department of Laparoscopic Surgery, Minimally Invasive Surgery Centre, Avda. Universidad s/n, 10071, Cáceres, Spain.
Surg Endosc. 2007 Jan;21(1):136-9. doi: 10.1007/s00464-005-0798-x. Epub 2006 Nov 16.
The efficacy of laparoscopic surgery in the treatment of chronic duodenal ulcer has been demonstrated using minimally invasive approaches. This study aimed to evaluate the technical feasibility of laparoscopic Finney pyloroplasty in six dogs. Under laparoscopic guidance, the anastomosis was created using mechanical devices (n = 3) and combining a linear stapler device and intracorporeal suturing (n = 3). The operative time and complications were recorded. Evaluation of the anastomosis included studies of intraoperative and postoperative endoscopy and ultrasonography as well as the complete gastric emptying time. The animals were killed 4 weeks after surgery. Measurement of luminal diameter, amount of adhesion formation, degree of healing, and inflammation or fibrosis were evaluated in the postmortem studies. The operation was successfully completed for all the animals. No intraoperative or postoperative complications were observed. Gastric emptying was significantly enhanced in the postoperative period, as compared with the preoperative results. After 1 month, there was no evidence of anastomotic leak dehiscence at the gastroduodenal anastomosis. Luminal diameter was increased, and no abnormal findings were encountered during the postmortem abdominal exploration. The technical feasibility of performing a safe laparoscopic pyloroplasty in a dog model was demonstrated in this study.
采用微创方法已证实腹腔镜手术治疗慢性十二指肠溃疡的疗效。本研究旨在评估6只犬行腹腔镜芬尼幽门成形术的技术可行性。在腹腔镜引导下,使用机械装置(n = 3)以及联合线性吻合器装置和体内缝合(n = 3)进行吻合。记录手术时间和并发症。吻合口评估包括术中和术后内镜检查及超声检查,以及完整的胃排空时间研究。术后4周处死动物。在尸检研究中评估管腔直径、粘连形成量、愈合程度以及炎症或纤维化情况。所有动物手术均成功完成。未观察到术中和术后并发症。与术前结果相比,术后胃排空明显加快。1个月后,胃十二指肠吻合口未见吻合口漏裂开迹象。管腔直径增大,尸检腹部探查未发现异常。本研究证实了在犬模型中进行安全的腹腔镜幽门成形术的技术可行性。