Hocking Jane S, Willis Jessika, Tabrizi Sepehr, Fairley Christopher K, Garland Suzanne M, Hellard Margaret
School of Population Health, University of Melbourne, Victoria 3010, Australia.
Sex Health. 2006 Dec;3(4):235-40. doi: 10.1071/sh06033.
To estimate the population-based chlamydia prevalence among women aged 18 to 35 years living in Melbourne, Victoria, and to assess the feasibility of using mailed urine specimens to test women.
A simple random sample of 11,001 households in Melbourne was selected from the telephone directory. Participants completed telephone interviews and provided urine specimens through the mail for chlamydia testing. Urines were tested using polymerase chain reaction.
11,001 households were contacted, with 1532 households identified as including eligible women; telephone interviews were completed, with 979 women giving a response rate of 64%. Six hundred and fifty-seven women provided a urine specimen with a response rate of 43%. Among sexually active women aged 18-24 years, the chlamydia prevalence was 3.7% (95% CI: 1.2%, 8.4%) and 0.2% (95% CI: 0.0%, 1.1%) among 25-35 year olds. Chlamydia prevalence increased significantly with an increasing number of male sexual partners.
This is the first study of its kind in Australia and shows that chlamydia prevalence increases with an increasing number of male sexual partners in the last 12 months. Mailed urine specimens are feasible for conducting population-based chlamydia-prevalence surveys but it is difficult to obtain high response rates with this methodology. Public health resources should now be directed towards investigating how to reach young women at increased risk of infection, ensuring that they are tested for chlamydia.
评估居住在维多利亚州墨尔本的18至35岁女性人群中衣原体感染率,并评估使用邮寄尿液样本对女性进行检测的可行性。
从电话簿中随机抽取墨尔本11,001户家庭作为简单随机样本。参与者完成电话访谈,并通过邮件提供尿液样本进行衣原体检测。尿液样本采用聚合酶链反应进行检测。
共联系了11,001户家庭,其中1532户家庭中有符合条件的女性;完成了电话访谈,979名女性做出回应,回应率为64%。657名女性提供了尿液样本,回应率为43%。在18至24岁的性活跃女性中,衣原体感染率为3.7%(95%可信区间:1.2%,8.4%),25至35岁女性中为0.2%(95%可信区间:0.0%,1.1%)。衣原体感染率随男性性伴侣数量的增加而显著上升。
这是澳大利亚同类研究中的首例,表明在过去12个月中,衣原体感染率随男性性伴侣数量的增加而上升。邮寄尿液样本对于开展基于人群的衣原体感染率调查是可行的,但用这种方法很难获得高回应率。公共卫生资源现在应致力于研究如何接触感染风险增加的年轻女性,确保她们接受衣原体检测。