Tobisu K
Urology Division, National Cancer Center Hospital.
Gan To Kagaku Ryoho. 1991 Jun;18(7):1221-6.
The ideal course of multidisciplinary treatment of disseminated germ cell tumors was shown with special reference to the role of the tumor markers for 1) diagnosis of pathological elements and risk factors, 2) appropriate selection of the protocol before and during the chemotherapeutic treatment, 3) timely resection of residual tumor and 4) monitoring of the recurrence after treatment. The practical role of tumor markers for evaluation of chemotherapeutic effectiveness, the following reconsideration of the appropriate protocol and timely indication of surgical intervention for residual mass after chemotherapy were emphasized by demonstrating the clinical courses of 2 patients with advanced nonseminomatous testicular germ cell tumors.
本文特别参考肿瘤标志物在以下方面的作用,展示了播散性生殖细胞肿瘤多学科治疗的理想过程:1)病理成分和危险因素的诊断;2)化疗前和化疗期间方案的合理选择;3)残余肿瘤的及时切除;4)治疗后复发的监测。通过展示2例晚期非精原细胞性睾丸生殖细胞肿瘤患者的临床病程,强调了肿瘤标志物在评估化疗疗效、随后对合适方案的重新考量以及化疗后残余肿块手术干预的适时指征方面的实际作用。