泰国曼谷一群交警样本中的高姐妹染色单体交换率。

High sister chromatid exchange among a sample of traffic policemen in Bangkok, Thailand.

作者信息

Soogarun Suphan, Suwansaksri Jamsai, Wiwanitkit Viroj

机构信息

Clinical Microscopy Research Unit, Department of Clinical Microscopy, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand.

出版信息

Southeast Asian J Trop Med Public Health. 2006 May;37(3):578-80.

PMID:17120983

Abstract

There are several volatile substances from the traffic, including benzene, toluene, carbon monoxide, lead and formaldehyde. Most of these substances are considered carcinogens. Police are at occupational risk for toxic fume exposure. This study compared sister chromatid exchange (SCE), a marker for genotoxicity, among a sample of Thai traffic policemen in Bangkok with healthy control subjects. Thirty police officers (all male) and 20 controls were included in this study. The average (mean+/-SD) SCE for policemen and controls were 4.40+/-0.93/cell and 0.24+/-0.12/cell, respectively. A significantly higher SCE among the policemen was observed. Concern for and prevention of toxic substance exposure in traffic police officers should be made a national goal.

摘要

交通中存在多种挥发性物质，包括苯、甲苯、一氧化碳、铅和甲醛。这些物质大多被视为致癌物。警察面临有毒烟雾暴露的职业风险。本研究比较了曼谷泰国交通警察样本与健康对照受试者之间作为遗传毒性标志物的姐妹染色单体交换（SCE）情况。本研究纳入了30名警察（均为男性）和20名对照。警察和对照的平均（均值±标准差）SCE分别为4.40±0.93/细胞和0.24±0.12/细胞。观察到警察的SCE显著更高。应将关注和预防交通警察接触有毒物质作为一项国家目标。