Guettier Jean-Marc, Gorden Phillip
National Institute of Diabetes and Digestive and Kidney Disease, National Institutes of Health, Bethesda, MD 20892, USA.
Endocrinol Metab Clin North Am. 2006 Dec;35(4):753-66, viii-ix. doi: 10.1016/j.ecl.2006.09.005.
Under physiologic conditions, glucose plays a critical role in providing energy to the central nervous system. A precipitous drop in the availability of this substrate results in dramatic symptoms that signal a medical emergency and warrant immediate therapy aimed at restoring plasma glucose to normal levels. A systemic approach to the differential diagnosis is useful in identifying the cause of hypoglycemia. Once established, a specific and/or definitive intervention that addresses that underlying problem can be implemented. In most cases, this systemic approach to diagnosis and therapy is rewarded with a good outcome for the patient.
在生理条件下,葡萄糖在为中枢神经系统提供能量方面起着关键作用。这种底物可用性的急剧下降会导致显著症状,这些症状表明是医疗紧急情况,需要立即进行旨在将血浆葡萄糖恢复到正常水平的治疗。采用系统方法进行鉴别诊断有助于确定低血糖的原因。一旦确定病因,就可以实施针对潜在问题的具体和/或确定性干预措施。在大多数情况下,这种系统的诊断和治疗方法会给患者带来良好的治疗效果。