Kim Sung-Wan, Yoon Jin-Sang, Choi Sung-Ku
Department of Psychiatry, Chonnam National University Medical School and Clinical Trial Center, Chonnam National University Hospital, Kwangju, Republic of Korea.
Hum Psychopharmacol. 2006 Dec;21(8):533-7. doi: 10.1002/hup.812.
This study evaluated the partial adherence to medication in schizophrenic patients in Korea.
The Adherence in Schizophrenia (ADHES) survey was conducted worldwide, including Asian countries. Through questionnaires for clinicians, caregivers and patients, information about medication adherence in patients with schizophrenia and factors affecting adherence were identified. This survey involved 131 psychiatrists from 80 psychiatry clinics and 2824 patients with schizophrenia were enrolled.
Partial adherence in patients with schizophrenia was prevalent (over 60%) in Korea. From the psychiatrists' point of view, the most prevalent factors associated with partial adherence in their patients were poor awareness of the illness (85%) and embarrassment at having to take medication daily (80%). Psychiatrists believed that most patients (83%) needed help from someone to remind them to take the medication regularly. Of patients, 57% reported feeling upset at having to take medication daily and 76% of caregivers reported preferring long-acting medications.
Based on the study results, a specific strategy to deal successfully with the prevalent partial adherence to medication in patients with schizophrenia should be developed, and long-acting medication may be one solution to improve partial adherence problems.
本研究评估了韩国精神分裂症患者的部分药物依从性情况。
“精神分裂症依从性（ADHES）调查”在全球范围内开展，包括亚洲国家。通过针对临床医生、护理人员和患者的问卷，确定了精神分裂症患者的药物依从性信息以及影响依从性的因素。该调查涉及来自80家精神病诊所的131名精神科医生，共招募了2824名精神分裂症患者。
在韩国，精神分裂症患者的部分依从性情况普遍存在（超过60%）。从精神科医生的角度来看，其患者中与部分依从性相关的最普遍因素是对疾病认识不足（85%）以及因每日需服药而感到尴尬（80%）。精神科医生认为，大多数患者（83%）需要他人帮助来提醒他们定期服药。患者中，57%报告因每日需服药而感到烦恼，76%的护理人员表示更喜欢长效药物。
基于研究结果，应制定一项具体策略，以成功应对精神分裂症患者中普遍存在的部分药物依从性问题，长效药物可能是改善部分依从性问题的一种解决方案。
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