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腹主动脉瘤合并恶性肿瘤:如何治疗?

Abdominal aortic aneurysm and concomitant malignancy: what treatment?

作者信息

Suffat Luca Panier, Guffanti Paolo, Rebecchi Fabrizio, Suffat Pietro Panier, Morino Francesco

机构信息

Dipartimento di Discipline Medico Chirurgiche, Sezione Universitaria di Chirurgia Generale ed Oncologica, Università degli Studi di Torino, Torino.

出版信息

Ann Ital Chir. 2006 Jul-Aug;77(4):345-9.

Abstract

UNLABELLED

The association of neoplasm and abdominal aortic aneurysm (AAA), although rare, may represents a therapeutic dilemma.

MATERIALS AND METHODS

Between January 1990 and December 2004 in our departement 127 patients were submitted because of an AAA, in 8 cases there was an association with a neoplasm, in the greater part being a colon cancer. In 3 cases we performed a one stage surgery, in 1 case the chose was for a two stage surgery, for 3 patients we opted for an endovascular treatment by an endograft, in 1 case a pancreatic cancer was diagnosed 3 months after the prosthetic replacement of an AAA and there were no surgical indications because of the patient was in an advanced neoplastic stage.

RESULTS

There weren't any prosthetic infection or more serious complications. The endovascular treatments were performed successfully without complications after few days being followed by cancer's resection.

DISCUSSION

In case of this association the prognosis is related to neoplasm's stage. Timing depednds on the pathology that has the higher risk of short-term complication. Since Nineties author's reports in Literature about one stage surgery are more frequent, while now endovascular methods open new chances.

CONCLUSIONS

One stage surgery is a safe option in case of association between AAA and cancer. We think that a good porpouse is the use of a vascular endograft in aneurysmal treatment followed, after few days, by cancer's resection.

摘要

未标注

肿瘤与腹主动脉瘤(AAA)的关联虽然罕见,但可能带来治疗难题。

材料与方法

1990年1月至2004年12月期间,我们科室有127例因腹主动脉瘤前来就诊的患者,其中8例合并有肿瘤,大部分为结肠癌。3例患者接受了一期手术,1例选择了二期手术,3例患者选择了通过血管内支架进行血管内治疗,1例患者在腹主动脉瘤人工血管置换术后3个月被诊断出患有胰腺癌,由于患者处于肿瘤晚期,没有手术指征。

结果

未发生人工血管感染或更严重的并发症。血管内治疗成功实施,术后几天无并发症,随后进行了癌症切除。

讨论

对于这种关联情况,预后与肿瘤分期有关。时机取决于具有较高短期并发症风险的病理情况。自九十年代以来,文献中作者关于一期手术的报道更为频繁,而现在血管内方法带来了新的机会。

结论

对于腹主动脉瘤与癌症的关联,一期手术是一种安全的选择。我们认为,一个好的做法是在动脉瘤治疗中使用血管内支架,几天后再进行癌症切除。

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