Yano Shinya, Motoyoshi Mituru, Uemura Miwa, Ono Akiko, Shimizu Noriyoshi
Department of Orthodontics, Nihon University School of Dentistry, Tokyo, Japan.
Eur J Orthod. 2006 Dec;28(6):541-6. doi: 10.1093/ejo/cjl044.
The aim of this study was to investigate the initial stability of tapered orthodontic miniscrews (T-type screws) after placement, the necessity of a healing period, and the propriety of immediate loading. Twenty male Wistar rats with a mean age of 20 weeks were divided into two groups. In the immediate-loading groups, straight orthodontic miniscrews (S-type screws) and T-type screws (five rats each) underwent experimental traction force for 2 weeks (W) immediately after placement. In the healing groups (S- and T-type, five rats each), force was applied for 2 W after a 6-W healing period. The right tibia in each rat was identified as the test limb, while the left tibia in each rat was used as the control group, and underwent no experimental force during the experimental period. The screw-to-bone contact was observed histologically and the bone-screw contact ratio was calculated. Scheffe's test was performed to compare the bone-screw contact ratio in each group using statistical software package (SPSS 8.0 for Windows). In the control group, the bone-screw contact ratio improved from 34.8 +/- 16.0 to 74.8 +/- 12.0 per cent with S-type screws in proportion to the experimental period (2 to 8 W, respectively). With the T-type screws in the test group, there was no significant difference between the immediate-loading and healing groups. In the immediate-loading group, the bone-screw contact ratio with T-type screws was significantly greater (82.3 +/- 15.0 per cent) than with the S-type screws (33.3 +/- 11.8 per cent; P < 0.05), suggesting that T-type screws can be used for orthodontic anchorage immediately after placement.
本研究旨在探讨锥形正畸微螺钉(T型螺钉)植入后的初始稳定性、愈合期的必要性以及即刻加载的适宜性。将20只平均年龄为20周的雄性Wistar大鼠分为两组。在即刻加载组中,直正畸微螺钉(S型螺钉)和T型螺钉(每组各5只大鼠)在植入后立即接受2周的实验牵引力。在愈合组(S型和T型,每组各5只大鼠)中,在6周的愈合期后施加2周的力。每只大鼠的右胫骨被确定为测试肢体,而每只大鼠的左胫骨用作对照组,在实验期间不施加实验力。通过组织学观察螺钉与骨的接触情况并计算骨-螺钉接触率。使用统计软件包(Windows版SPSS 8.0)进行Scheffe检验,以比较每组的骨-螺钉接触率。在对照组中,S型螺钉的骨-螺钉接触率随实验期(分别为2至8周)从34.8±16.0%提高到74.8±12.0%。在测试组中,对于T型螺钉,即刻加载组和愈合组之间没有显著差异。在即刻加载组中,T型螺钉的骨-螺钉接触率(82.3±15.0%)显著高于S型螺钉(33.3±11.8%;P<0.05),这表明T型螺钉在植入后可立即用于正畸锚固。