急性运动和训练对胰岛素作用及敏感性的影响：聚焦于肌肉中的分子机制。

Effects of acute exercise and training on insulin action and sensitivity: focus on molecular mechanisms in muscle.

作者信息

Wojtaszewski Jørgen F P, Richter Erik A

机构信息

Copenhagen Muscle Research Centre, Institute of Exercise and Sport Sciences, University of Copenhagen, Denmark.

出版信息

Essays Biochem. 2006;42:31-46. doi: 10.1042/bse0420031.

DOI:10.1042/bse0420031

PMID:17144878

Abstract

A single bout of exercise increases insulin sensitivity for several hours and the effect is mainly restricted to the muscles recruited during exercise. When exercise is repeated over time, adaptations to physical training occur that include more long-lasting increases in insulin sensitivity. The present review explores the molecular mechanisms involved in both the acute and chronic effects of exercise on insulin sensitivity in skeletal muscle.

摘要

单次运动可提高胰岛素敏感性达数小时，且这种效应主要局限于运动时参与的肌肉。随着时间推移反复进行运动，会出现对体育锻炼的适应性变化，包括胰岛素敏感性更持久的提高。本综述探讨了运动对骨骼肌胰岛素敏感性的急性和慢性影响所涉及的分子机制。