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单中心对血流动力学不稳定和稳定的腹主动脉瘤破裂患者进行开放手术和血管腔内治疗的经验。

A single-center experience in open and endovascular treatment of hemodynamically unstable and stable patients with ruptured abdominal aortic aneurysms.

作者信息

Coppi Gioacchino, Silingardi Roberto, Gennai Stefano, Saitta Giuseppe, Ciardullo Anna Vittoria

机构信息

Department of Vascular Surgery, Policlinico Hospital of Modena and University of Studies of Modena and Reggio Emilia, Modena, Italy.

出版信息

J Vasc Surg. 2006 Dec;44(6):1140-7. doi: 10.1016/j.jvs.2006.08.070.

Abstract

OBJECTIVE

To retrospectively compare a single center's immediate and mid-term outcomes of ruptured abdominal aortic aneurysm open and endovascular repair (EVAR) for two patient groups-hemodynamically stable and unstable patients-in the same time period.

METHODS

Patients presenting at our center with confirmed rupture of an abdominal aortic aneurysm between December 1999 and April 2006 were considered according to an intention-to-treat model with EVAR. Patients with symptomatic or acute (but not ruptured) AAAs were not included in this study. Thirty-three patients underwent EVAR, and 91 underwent open repair. Seventy-two patients (EVAR, 45%; open, 63%) were classified as hemodynamically unstable at arrival, and 52 were classified as stable (EVAR, 55%; open, 37%). Ninety-seven percent of EVAR procedures commenced under local anesthesia, and 100% of open repairs occurred with general anesthesia. Overall successful graft deployment, 30-day mortality, overall reintervention rate, and complications were the study primary end points.

RESULTS

Overall successful graft deployment for EVAR was 91%; for open repair, it was 96%. Overall 30-day mortality for EVAR was 30% (unstable, 53%; stable, 11%), and the rate was 46% for open repair (unstable, 61%; stable, 21%). The EVAR postoperative reintervention rate (within 30 days) was 15% (unstable, 20%; stable, 11%), and for open repair it was 10% (unstable, 9%; stable, 15%). We recorded a 27% severe complication rate for EVAR patients (unstable, 40%; stable, 17%), and for patients treated with open repair, it was 33% (unstable, 35%; stable, 29%). Our overall EVAR eligibility rate was 52%, and our overall EVAR treatment rate was 27%.

CONCLUSIONS

Our study's overall results for EVAR remain encouraging when compared with those of conventional repair, but large randomized trials are required to confirm the efficacy of the procedure.

摘要

目的

回顾性比较同一时期内,一家单中心针对血流动力学稳定和不稳定的两组患者,采用开放手术和血管腔内修复术(EVAR)治疗破裂腹主动脉瘤的近期和中期疗效。

方法

依据意向性治疗模型,纳入1999年12月至2006年4月间在本中心确诊为腹主动脉瘤破裂的患者。有症状或急性(但未破裂)腹主动脉瘤患者不纳入本研究。33例患者接受了EVAR治疗,91例接受了开放手术修复。72例患者(EVAR组占45%;开放手术组占63%)入院时被分类为血流动力学不稳定,52例被分类为稳定(EVAR组占55%;开放手术组占37%)。97%的EVAR手术在局部麻醉下开始,100%的开放手术在全身麻醉下进行。总体移植物成功植入率、30天死亡率、总体再次干预率和并发症是本研究的主要终点。

结果

EVAR总体移植物成功植入率为91%;开放手术修复为96%。EVAR总体30天死亡率为30%(不稳定患者为53%;稳定患者为11%),开放手术修复的死亡率为46%(不稳定患者为61%;稳定患者为21%)。EVAR术后(30天内)再次干预率为15%(不稳定患者为20%;稳定患者为11%),开放手术修复为10%(不稳定患者为9%;稳定患者为15%)。我们记录到EVAR患者严重并发症发生率为27%(不稳定患者为40%;稳定患者为17%),接受开放手术修复的患者为33%(不稳定患者为35%;稳定患者为29%)。我们的总体EVAR适用率为52%,总体EVAR治疗率为27%。

结论

与传统修复方法相比,我们研究中EVAR的总体结果仍然令人鼓舞,但需要大型随机试验来证实该手术的疗效。

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