Andersen Stig Ejdrup
H:S Bispebjerg Hospital, Klinisk Farmakologisk Enhed, København NV.
Ugeskr Laeger. 2006 Nov 27;168(48):4185-8.
Most Danish hospitals have ward-based medication supply systems: frequently used drugs are stored in ward drug cupboards and dispensed by nursing staff. The objective of this study was to describe the frequency of dispensing errors and to identify risk factors.
Cross-sectional study conducted on five hospital wards. Random samples of dispensed drugs were compared to the written drug orders.
In total, 619 (94.4%) of the 656 samples were dispensed correctly (95% CI 92.3 to 95.9%). Among 2360 opportunities for error (2336 dispensed plus 24 prescribed but not dispensed doses), 42 errors were detected, error rate 1.8% (95% CI 1.3 to 2.4%). 55% of all errors were omissions. Logistic regression analysis revealed that dispensing errors were associated with the scheduled administration time, the ward and the number of dispensed doses. Having one rather than two nurses dispensing and administering drugs did not affect the error rate.
For each scheduled time, approximately 19 of 20 patients' drugs are correctly dispensed. Although the clinical significance of errors was not rated, the advantage of having one rather than two nurses dispensing and administering is dubious. Reducing poly-pharmacy, however, might reduce the error rate and this strategy should be tested in a prospective study. As a direct consequence of this study, emphasis will be placed on analysing and learning procedures from wards with low error rates.
大多数丹麦医院采用基于病房的药品供应系统:常用药物存放在病房药柜中,由护理人员发放。本研究的目的是描述发放错误的频率并识别风险因素。
对五个医院病房进行横断面研究。将发放药品的随机样本与书面医嘱进行比较。
在656个样本中,共有619个(94.4%)发放正确(95%置信区间92.3%至95.9%)。在2360次出错机会(2336次已发放加上24次已开处方但未发放的剂量)中,检测到42次错误,错误率为1.8%(95%置信区间1.3%至2.4%)。所有错误中有55%是遗漏。逻辑回归分析显示,发放错误与预定给药时间、病房以及发放剂量数量有关。由一名而非两名护士发放和给药并不会影响错误率。
对于每个预定时间,约20名患者中有19名的药物发放正确。尽管未对错误的临床意义进行评估,但由一名而非两名护士发放和给药的优势值得怀疑。然而,减少联合用药可能会降低错误率,这一策略应在前瞻性研究中进行测试。作为本研究的直接结果,将重点分析错误率低的病房的流程并从中学习。