Secrist John A
Southern Research Institute, Birmingham, AL, USA.
Nucleic Acids Symp Ser (Oxf). 2005(49):15-6. doi: 10.1093/nass/49.1.15.
The continuing use of nucleosides as anticancer agents is discussed. Examples include the newly approved drug clofarabine as well as 4'-thio-ara-C, a drug that has initiated clinical trials. New directions in anticancer drug discovery will also be discussed.