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既往应激试验结果为阴性对急诊科胸痛综合征患者中急诊医师处置决策的影响。

Impact of a negative prior stress test on emergency physician disposition decision in ED patients with chest pain syndromes.

作者信息

Nerenberg Rebecca H, Shofer Frances S, Robey Jennifer L, Brown Aaron M, Hollander Judd E

机构信息

Department of Emergency Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA.

出版信息

Am J Emerg Med. 2007 Jan;25(1):39-44. doi: 10.1016/j.ajem.2006.05.027.

Abstract

OBJECTIVE

Many emergency department (ED) patients with potential acute coronary syndromes (ACS) have prior visits and prior cardiac testing; however, the effect of knowledge of prior testing on the emergency physician disposition decision making is not known. We studied the impact of prior noninvasive testing (ie, stress testing) for myocardial ischemia on disposition decision making in ED patients with potential ACS.

METHODS

We performed a prospective cohort study of ED patients with chest pain who received an electrocardiogram for potential ACS. Data included demographics, medical history, stress test history, and TIMI risk score. Patients were followed in-house; 30-day telephone interviews were performed for follow-up. Main outcomes were ED disposition (admit/discharge) and a composite of 30-day death, acute myocardial infarction, and revascularization stratified on the basis of prior stress testing known at the time of presentation. Standard statistical techniques were used with 95% confidence intervals (CI).

RESULTS

There were 1853 patients enrolled and 97% had follow-up. Patients had a mean age of 53 +/- 14 years; 60% were women, 67% were black. There were 1491 (79%) patients without a prior stress test, 291 (16%) had a normal prior stress test result, and 89 (5%) had an abnormal prior stress test result. Admission rates were 92% (95% CI, 87%-98%) for patients with a prior abnormal stress test, 73% (95% CI, 67%-78%) for patients with a normal prior stress test, and 70% (95% CI, 67%-72%) for patients without a prior stress test. Adverse outcomes were the highest among patients with prior abnormal stress test but did not differ significantly between patients with no prior stress test and patients with prior normal stress test (10.1% [95% CI, 3.6-16.7%] vs 5.2% [95% CI, 4.1-6.4%] vs 4.8% [95% CI, 2.4-7.3%]).

CONCLUSION

Patients without prior stress tests and patients with prior normal stress tests were admitted for potential ACS at the same rate and had the same 30-day cardiovascular event rates. This suggests that prior stress testing does not affect subsequent disposition decisions. Perhaps cardiac catheterization or computed tomography coronary angiograms would have more of an impact on subsequent visits, making them potentially more cost-effective in the low-risk patient.

摘要

目的

许多急诊科(ED)潜在急性冠状动脉综合征(ACS)患者有既往就诊史和既往心脏检查;然而,既往检查结果的知晓对急诊医生处置决策的影响尚不清楚。我们研究了既往心肌缺血无创检查(即负荷试验)对潜在ACS的ED患者处置决策的影响。

方法

我们对因潜在ACS接受心电图检查的胸痛ED患者进行了一项前瞻性队列研究。数据包括人口统计学、病史、负荷试验史和TIMI风险评分。患者在医院内接受随访;进行30天电话随访。主要结局是ED处置(入院/出院)以及根据就诊时已知的既往负荷试验分层的30天死亡、急性心肌梗死和血运重建的复合结局。使用标准统计技术及95%置信区间(CI)。

结果

共纳入1853例患者,97%有随访。患者平均年龄53±14岁;60%为女性,67%为黑人。1491例(79%)患者无既往负荷试验,291例(16%)既往负荷试验结果正常,89例(5%)既往负荷试验结果异常。既往负荷试验异常的患者入院率为92%(95%CI,87%-98%),既往负荷试验正常的患者入院率为73%(95%CI,67%-78%),无既往负荷试验的患者入院率为70%(95%CI,67%-72%)。既往负荷试验异常的患者不良结局最高,但无既往负荷试验的患者与既往负荷试验正常的患者之间无显著差异(10.1%[95%CI,3.6-16.7%]对5.2%[95%CI,4.1-6.4%]对4.8%[95%CI,2.4-7.3%])。

结论

无既往负荷试验的患者和既往负荷试验正常的患者因潜在ACS入院率相同,30天心血管事件发生率相同。这表明既往负荷试验不影响后续处置决策。或许心脏导管检查或计算机断层扫描冠状动脉造影对后续就诊影响更大,使其在低风险患者中可能更具成本效益。

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