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[活体亲属肝移植中胆道解剖的研究]

[Study of biliary anatomy in living related liver transplantation].

作者信息

Soares Renato Vianna, Coelho Júlio Cezar U, Matias Jorge E F, de Freitas Alexandre C T, Zeni-Neto Clementino, de Godoy José Luis

机构信息

Serviço de Transplante Hepático, Universidade Federal do Paraná, Curitiba, PR.

出版信息

Arq Gastroenterol. 2006 Jul-Sep;43(3):173-7. doi: 10.1590/s0004-28032006000300004.

Abstract

BACKGROUND

Anatomic variations of the biliary tree are frequent and increase complications after liver transplantation.

AIM

To describe the anatomy of the bile ducts of donors and recipients of living related liver transplantation.

METHODS

From March 1998 to September 2002, the study was retrospective (23 transplantations). From October 2002 to August 2003, the study was prospective (17 transplantations). We studied the hepatic anatomy of 80 consecutive patients (40 donors and 40 recipients) of the living-related liver transplantation program of the "Hospital de Clínicas da Universidade Federal do Paraná" and the "Hospital Nossa Senhora das Graças", Curitiba, PR, Brazil; 51 were male (27 recipients 24 donors) and 29 female (13 recipients and 16 donors). The median age among the donors was 32.6 years and among the recipients was 36.3 years. Thirty-two recipients were adults and 8 recipients were under 15 years old. The bile duct anatomy was studied by magnetic resonance cholangiography in 33 patients, and anomalies were seen in 3 of them (9.1%).

RESULTS

The most prevalent variation of bile ducts was the fusion of the right posterior duct with the left duct (6.06%; n=2). In the 40 harvesting operations, the right bile duct was single in 25 patients (87.5%), among the 32 right-lobe donors, double in 2 (6.25%) and triple in 2 (6.25%). All of the eight left livers procured had single bile ducts. Among the 40 recipients, the common bile duct was bifurcated in 2 of them (5%).

CONCLUSION

The prevalence of biliary anomalies is high in patients subjected to living liver transplantation and some anomalies are not diagnosed with preoperative imaging exams.

摘要

背景

胆管的解剖变异很常见,会增加肝移植后的并发症。

目的

描述活体肝移植供体和受体胆管的解剖结构。

方法

1998年3月至2002年9月,该研究为回顾性研究(23例移植)。2002年10月至2003年8月,该研究为前瞻性研究(17例移植)。我们研究了巴西巴拉那联邦大学临床医院和库里蒂巴圣母格拉西亚医院活体肝移植项目中连续80例患者(40例供体和40例受体)的肝脏解剖结构;51例为男性(27例受体和24例供体),29例为女性(13例受体和16例供体)。供体的中位年龄为32.6岁,受体的中位年龄为36.3岁。32例受体为成年人,8例受体年龄在15岁以下。33例患者通过磁共振胆管造影研究胆管解剖结构,其中3例(9.1%)发现异常。

结果

胆管最常见的变异是右后胆管与左胆管融合(6.06%;n = 2)。在40例取肝手术中,25例患者(87.5%)的右胆管为单支,在32例右叶供体中,2例(6.25%)为双支,2例(6.25%)为三支。获取的8例左肝均为单支胆管。在40例受体中,2例(5%)的胆总管分叉。

结论

活体肝移植患者胆管异常的发生率较高,一些异常术前影像学检查未能诊断出来。

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