Palmer Robert M, Lokey Jonathan S
Greenville Memorial Hospital, Greenville Hospital System, 701 Grove Road, Greenville, SC 29605, USA.
Am J Surg. 2006 Dec;192(6):865-8. doi: 10.1016/j.amjsurg.2006.08.059.
Minimally invasive parathyroidectomy (MIPX) hinges on accurate preoperative localization and the intraoperative parathyroid hormone (IOPTH) assay to confirm adequate resection. Our goal was to evaluate the results of this technique when applied in a nonuniversity setting.
All patients undergoing parathyroidectomy at our institution from August 2000 until June 2005 were retrospectively reviewed. Patients were divided into 2 groups: bilateral cervical exploration versus MIPX based on adequate preoperative localization.
There were 271 patients who underwent parathyroidectomy during the study period. Of these cases, 204 patients with primary hyperparathyroidism composed our study group. We observed that 136 patients (67%) had unilaterally positive localization studies (group 1), and MIPX was successfully completed in 52% of cases.
Although nearly all patients with single-gland disease should be candidates for MIPX, we found that adequate preoperative imaging and concurrent thyroid disease limited successful completion of the minimally invasive procedure.
微创甲状旁腺切除术(MIPX)依赖于准确的术前定位和术中甲状旁腺激素(IOPTH)检测以确认切除充分。我们的目标是评估该技术在非大学附属医院环境中应用时的效果。
回顾性分析2000年8月至2005年6月在我院接受甲状旁腺切除术的所有患者。根据术前定位是否充分,将患者分为两组:双侧颈部探查组和MIPX组。
在研究期间有271例患者接受了甲状旁腺切除术。其中,204例原发性甲状旁腺功能亢进患者构成了我们的研究组。我们观察到136例患者(67%)单侧定位检查呈阳性(第1组),其中52%的病例成功完成了MIPX。
虽然几乎所有单发性甲状旁腺疾病患者都应是MIPX的候选对象,但我们发现术前影像学检查不充分和并存甲状腺疾病限制了微创操作的成功完成。