各种惰性气体在大鼠骨骼肌中的溶解度。

Solubility of various inert gases in rat skeletal muscle.

作者信息

Carles A C, Kawashiro T, Piiper J

出版信息

Pflugers Arch. 1975 Sep 9;359(3):209-18. doi: 10.1007/BF00587380.

Abstract

For the determination of solubility coefficients, isolated rat abdominal muscles were equilibrated at 37 degrees C with various inert gases saturated with water vapor. After rapid transfer into a closed chamber containing room air the amount of gas extracted from the sample by diffusion was measured by gas chromatography. Corrections for unextracted gas and for gas lost during the transfer of the sample were applied. The following mean values for the solubility coefficients, in mumol-1(-1)-torr(-1), were found: chloro-difluoro-methane (Freon 22), 56.0; acetylene, 55.5; nitrous oxide, 27.7; methane, 2.42; hydrogen, 1.13; helium, 0.608; sulfur hexafluoride, 0.559. The relationships between solubility in tissue, in water and in olive oil are discussed.

摘要

为了测定溶解度系数，将分离出的大鼠腹部肌肉在37摄氏度下与各种饱和了水蒸气的惰性气体达到平衡。在迅速转移至含有室内空气的密闭腔室后，通过气相色谱法测量样品因扩散而逸出的气体量。对未逸出的气体以及样品转移过程中损失的气体进行了校正。得到了以下以μmol⁻¹·torr⁻¹为单位的溶解度系数平均值：氯二氟甲烷（氟利昂22），56.0；乙炔，55.5；一氧化二氮，27.7；甲烷，2.42；氢气，1.13；氦气，0.608；六氟化硫，0.559。讨论了在组织、水和橄榄油中的溶解度之间的关系。