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腹膜闪烁扫描术在持续性非卧床腹膜透析并发症检测中的作用

The role of peritoneal scintigraphy in the detection of continuous ambulatory peritoneal dialysis complications.

作者信息

Tokmak Handan, Mudun Ayşe, Türkmen Cuneyt, Sanli Yasemin, Cantez Sema, Bozfakioğlu Semra

机构信息

Department of Nuclear Medicine, Istanbul University, Istanbul Medical Faculty, Capa, Istanbul 34390, Turkey.

出版信息

Ren Fail. 2006;28(8):709-13. doi: 10.1080/08860220600925396.

Abstract

While continuous ambulatory peritoneal dialysis (CAPD) offers several advantages over hemodialysis in patients with end-stage renal disease, several complications have been recognized. The intraperitoneal instillation of dialysate increases intra-abdominal pressure and consequently predisposes the patient to leaks and herniations through defects in the abdominal wall. The use of an intraperitoneal radiolabeled colloid has been previously described to image entities such as hernias, patent processus vaginalis, abdominal wall, and diaphragmatic leakage. This study shows a simple, non-invasive method of determining the site of dialysate leak and its importance to assist further patient management. There has been a continuing increase in the number of end stage renal disease patients maintained on chronic peritoneal dialysis (CPD). Many patients choose CPD as their preferred chronic dialysis treatment, though approximately 20% of patients who drop out transfer to hemodialysis annually.[1] Although peritonitis remains the major reason for transfer to hemodialysis, other factors such as exit site infections, catheter-related problems, abdominal wall and inguinal hernias, loss of ultrafiltrations, and poor clearance contribute to CPD technique failure.[2] In order to permit the continuation of long-term therapy with CPD, these complications should be resolved. Routine laboratory evaluation or physical examination can detect some CPD-related problems; however, some patients require more complicated investigations to evaluate their problems properly.

摘要

虽然持续性非卧床腹膜透析(CAPD)相较于血液透析为终末期肾病患者带来了诸多优势,但也已认识到一些并发症。向腹腔内注入透析液会增加腹内压,进而使患者因腹壁缺陷而易于出现渗漏和疝。此前已有使用腹腔内放射性标记胶体对诸如疝、鞘状突未闭、腹壁和膈肌渗漏等情况进行成像的描述。本研究展示了一种确定透析液渗漏部位的简单、非侵入性方法及其对辅助进一步患者管理的重要性。接受慢性腹膜透析(CPD)的终末期肾病患者数量持续增加。许多患者选择CPD作为其首选的慢性透析治疗方式,尽管每年约有20%退出的患者转而接受血液透析。[1]虽然腹膜炎仍是转为血液透析的主要原因,但其他因素如出口处感染、导管相关问题、腹壁和腹股沟疝、超滤丧失以及清除率不佳等也会导致CPD技术失败。[2]为了使CPD长期治疗得以持续,这些并发症应得到解决。常规实验室评估或体格检查能够检测出一些与CPD相关的问题;然而,一些患者需要更复杂的检查来恰当评估其问题。

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