部分性葡萄胎妊娠妇女清宫后宫内妊娠滋养细胞肿瘤的人绒毛膜促性腺激素水平及风险
Postevacuation hCG levels and risk of gestational trophoblastic neoplasia among women with partial molar pregnancies.
作者信息
Growdon Whitfield B, Wolfberg Adam J, Feltmate Colleen M, Goldstein Donald P, Genest David R, Chinchilla Manuel E, Berkowitz Ross S, Lieberman Ellice S
机构信息
Donald P. Goldstein, M.D., Trophoblastic Tumor Registry, New England Trophoblastic Disease Center, USA.
出版信息
J Reprod Med. 2006 Nov;51(11):871-4.
OBJECTIVE
To develop human chorionic gonadotropin (hCG) criteria that determine a patient's risk of developing persistent gestational trophoblastic neoplasia (GTN) or achieving remission after partial mole evacuation.
STUDY DESIGN
We used a database from the New England Trophoblastic Disease Center to analyze hCG levels from 284 women with partial molar pregnancies diagnosed between 1973 and 2003.
RESULTS
An hCG level >199 mIU/mL in the third through eighth week following molar evacuation was associated with at least a 35% risk of GTN.
CONCLUSION
Women with partial mole who have elevated hCG levels within the first few weeks after molar evacuation are at increased risk for developing GTN.
目的
制定人绒毛膜促性腺激素（hCG）标准，以确定患者发生持续性妊娠滋养细胞肿瘤（GTN）或在部分葡萄胎清宫后实现缓解的风险。
研究设计
我们使用了新英格兰滋养细胞疾病中心的数据库，分析了1973年至2003年间诊断为部分性葡萄胎妊娠的284名女性的hCG水平。
结果
葡萄胎清宫后第三至第八周，hCG水平>199 mIU/mL与至少35%的GTN风险相关。
结论
部分性葡萄胎女性在葡萄胎清宫后的头几周内hCG水平升高，发生GTN的风险增加。
Zotero 插件