Morell-Dubois S, Quéméneur T, Bourdon F, Lambert M, Queyrel V, Launay D, Hachulla E, Labalette P, Hatron P-Y
Service de médecine interne, hôpital Huriez, CHU de Lille, 59037 Lille cedex, France.
Rev Med Interne. 2007 Jan;28(1):33-7. doi: 10.1016/j.revmed.2006.09.020. Epub 2006 Oct 6.
Almost 50% of patients with Wegener's granulomatosis (WG) develop ocular features, leading to visual loss in 8%. However, central retinal artery occlusion (CRAO) has exceptionally been reported.
We report 2 patients with CRAO and WG according to ACR classification criteria. A literature search indicates that CRAO with WG has only been reported in 15 patients. We analyse the 17 cases to discuss systemic manifestations, ocular prognosis and treatment.
CRAO is a rare manifestation of WG. Nevertheless, CRAO seems to be associated with vasculitic type of WG. So, a prompt diagnosis could lead to early aggressive regimen to improve visual and general prognosis.