Baillard C, Bianchi A, Gehan G, Sitbon P, Denantes C, Benhamou D, Cupa M, Samama C-M
Départements d'anesthésie-réanimation, CHU Avicenne, EA 3409, 93009 Bobigny, France.
Ann Fr Anesth Reanim. 2007 Feb;26(2):132-5. doi: 10.1016/j.annfar.2006.09.003. Epub 2006 Dec 12.
This study was undertaken to quantify the use of chronic medication and herbal remedies in the presurgical population.
Prospective multicenter survey.
Adult patients presenting for anaesthesia were directly asked if they were currently using chronic medication or herbal remedies.
Among 1057 patients (age 54+/-17 yrs, woman 54%, ASA 2 [1-4], 74%) were taking one or more chronic medication. The most commonly used treatments were, in descending order angiotensin-converting enzyme inhibitors and angiotensin-II receptor blockers (15%), beta blockers (11%) and platelet inhibitors (10%). Also, 9% were taking one or more of the following herbal remedies known to interact with the perioperative period: valeriane, ginseng, ginkgo, St John's wort, echinacea and ephedra. Women and patients aged 40-70 yr were most likely to be taking a herbal product (p<0.001 and p<0.01 respectively).
Chronic medication and herbal remedies are common in patients presenting for anaesthesia. Because of the potential interactions between anaesthetic drugs or techniques and such medication it is important for anaesthetists to be aware of their use.
本研究旨在量化外科手术前患者群体中慢性药物和草药疗法的使用情况。
前瞻性多中心调查。
直接询问接受麻醉的成年患者是否正在使用慢性药物或草药疗法。
在1057例患者中(年龄54±17岁,女性占54%,美国麻醉医师协会分级2级[1 - 4级]者占74%),有74%正在服用一种或多种慢性药物。最常用的治疗药物按降序排列依次为血管紧张素转换酶抑制剂和血管紧张素II受体阻滞剂(15%)、β受体阻滞剂(11%)和血小板抑制剂(10%)。此外,9%的患者正在服用以下已知会与围手术期相互作用的一种或多种草药疗法:缬草、人参、银杏、圣约翰草、紫锥菊和麻黄。女性以及40 - 70岁的患者最有可能服用草药产品(分别为p<0.001和p<0.01)。
慢性药物和草药疗法在接受麻醉的患者中很常见。由于麻醉药物或技术与这类药物之间可能存在相互作用,麻醉医生了解其使用情况很重要。