Fulton Kate F, Bate Mark A, Faux Noel G, Mahmood Khalid, Betts Chris, Buckle Ashley M
The Department of Biochemistry and Molecular Biology, School of Biomedical Sciences, Faculty of Medicine, Monash University Clayton, Victoria 3800, Australia.
Nucleic Acids Res. 2007 Jan;35(Database issue):D304-7. doi: 10.1093/nar/gkl1007. Epub 2006 Dec 14.
The Protein Folding Database (PFD) is a publicly accessible repository of thermodynamic and kinetic protein folding data. Here we describe the first major revision of this work, featuring extensive restructuring that conforms to standards set out by the recently formed International Foldeomics Consortium. The database now adopts standards for data acquisition, analysis and reporting proposed by the consortium, which will facilitate the comparison of folding rates, energies and structure across diverse sets of proteins. Data can now be easily deposited using a rich set of deposition tools. Enhanced search tools allow sophisticated searching and graphical data analysis affords simple data analysis online. PFD can be accessed freely at http://www.foldeomics.org/pfd/.
蛋白质折叠数据库(PFD)是一个可公开访问的热力学和动力学蛋白质折叠数据存储库。在此,我们描述这项工作的首次重大修订,其特点是进行了广泛的结构调整,以符合最近成立的国际折叠组学联盟制定的标准。该数据库现在采用了联盟提出的数据采集、分析和报告标准,这将有助于比较不同蛋白质组的折叠速率、能量和结构。现在可以使用丰富的提交工具轻松提交数据。增强的搜索工具允许进行复杂搜索,而图形数据分析则提供了在线简单数据分析功能。可通过http://www.foldeomics.org/pfd/免费访问PFD。