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针对大学生的脑膜炎球菌性脑膜炎预防项目:文献综述

Meningococcal meningitis prevention programs for college students: a review of the literature.

作者信息

Butler Karen M

机构信息

College of Nursing, University of Kentucky, Lexington, KY 40536, USA.

出版信息

Worldviews Evid Based Nurs. 2006;3(4):185-93. doi: 10.1111/j.1741-6787.2006.00069.x.

Abstract

BACKGROUND AND PURPOSE

The incidence of meningococcal meningitis in college students is higher than in other populations. College students, especially 1st-year students living in dormitories or residence halls, are among those at highest risk of developing the disease. It is estimated that immunization can prevent up to 83% of cases among adolescents and college students. A review of the literature was undertaken to identify and critique the research-based prevention programs that are focused on college students.

METHOD

An extensive search of the Cochrane Database of systematic reviews, Medline, PubMed, and CINAHL was undertaken. The Journal of American College Health was hand searched, and bibliographies were reviewed for studies not otherwise identified. Four publications met the search criteria. These studies were reviewed and graded for level of evidence.

FINDINGS

One study could not be compared with the other three because of its lack of detail. Of the other three studies, two were descriptive and factors were identified that related to vaccination and nonvaccination in the college student population (both Evidence Grade C). Only one study was described that included an educational intervention, which resulted in increased vaccination rates in a college student population (Evidence Grade B).

CONCLUSIONS AND IMPLICATIONS

The published literature is severely limited in the area of meningococcal meningitis prevention programs in the at-risk college student population. A critical need exists for controlled studies to test the interventions that are most effective in this population as well as broader-based studies to further identify those students at increased risk for the disease as well as for nonvaccination.

摘要

背景与目的

大学生群体中脑膜炎球菌性脑膜炎的发病率高于其他人群。大学生,尤其是居住在宿舍的一年级学生,是罹患该疾病风险最高的人群之一。据估计,免疫接种可预防青少年和大学生中高达83%的病例。我们对文献进行了综述,以识别和评判针对大学生的基于研究的预防项目。

方法

我们对Cochrane系统评价数据库、Medline、PubMed和护理学与健康领域数据库进行了广泛检索。我们还手工检索了《美国大学健康杂志》,并查阅了参考文献以查找其他未被识别的研究。有四项出版物符合检索标准。我们对这些研究进行了综述,并根据证据水平进行了分级。

结果

由于一项研究缺乏细节,无法与其他三项进行比较。在其他三项研究中,两项为描述性研究,并确定了与大学生群体接种疫苗和未接种疫苗相关的因素(证据等级均为C级)。仅描述了一项包含教育干预措施的研究,该措施使大学生群体的疫苗接种率有所提高(证据等级为B级)。

结论与启示

在针对高危大学生群体的脑膜炎球菌性脑膜炎预防项目领域,已发表的文献极为有限。迫切需要进行对照研究,以测试对该群体最有效的干预措施,以及开展更广泛的研究,以进一步识别那些疾病风险增加以及未接种疫苗风险增加的学生。

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