Virtanen Marianna, Honkonen Teija, Kivimäki Mika, Ahola Kirsi, Vahtera Jussi, Aromaa Arpo, Lönnqvist Jouko
Finnish Institute of Occupational Health, Topeliuksenkatu 41 aA, FIN-00250 Helsinki, Finland.
J Affect Disord. 2007 Mar;98(3):189-97. doi: 10.1016/j.jad.2006.05.034. Epub 2006 Dec 19.
Population-based studies on the association between work stress and mental disorders are scarce, and it is not known whether work stress predicts mental disorders requiring treatment.
To examine the associations of work stress with DSM-IV mental disorders and subsequent antidepressant medication.
3366 participants from a representative sample of the Finnish working population responded to a survey (The Health 2000 Study). 12-month prevalence of depressive or anxiety disorders was examined with the Composite International Diagnostic Interview. Data on antidepressant prescriptions with a 3-year follow-up period were collected from a nationwide register of Social Insurance Institution.
In men and women, high job demands, low job control and high job strain were associated with 12-month prevalence of depressive or anxiety disorders. After adjustment for lifetime and baseline mental disorders, men with high job demands and high job strain had increased risk of future antidepressant medication.
Work stress is associated with mental disorders among both sexes and among men it is a risk factor for mental disorders treated with antidepressant medication.
基于人群的工作压力与精神障碍之间关联的研究较少，且尚不清楚工作压力是否能预测需要治疗的精神障碍。
研究工作压力与《精神疾病诊断与统计手册》第四版（DSM-IV）精神障碍及后续抗抑郁药物治疗之间的关联。
来自芬兰工作人群代表性样本的3366名参与者回应了一项调查（《2000年健康研究》）。采用综合国际诊断访谈来检查抑郁或焦虑障碍的12个月患病率。从全国社会保险机构登记册收集了为期3年随访期的抗抑郁药物处方数据。
在男性和女性中，高工作要求、低工作控制和高工作压力与抑郁或焦虑障碍的12个月患病率相关。在对终生和基线精神障碍进行调整后，高工作要求和高工作压力的男性未来使用抗抑郁药物的风险增加。
工作压力在男性和女性中均与精神障碍相关，且在男性中它是抗抑郁药物治疗的精神障碍的一个风险因素。
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