Demma Linda J, Traeger Marc, Blau Dianna, Gordon Rondeen, Johnson Brian, Dickson Jeff, Ethelbah Rudy, Piontkowski Stephen, Levy Craig, Nicholson William L, Duncan Christopher, Heath Karen, Cheek James, Swerdlow David L, McQuiston Jennifer H
Centers for Disease Control and Prevention, National Center for Infectious Diseases, Division of Viral and Rickettsial Diseases, Atlanta, Georgia, USA.
Vector Borne Zoonotic Dis. 2006 Winter;6(4):423-9. doi: 10.1089/vbz.2006.6.423.
During 2002 through 2004, 15 patients with Rocky Mountain spotted fever (RMSF) were identified in a rural community in Arizona where the disease had not been previously reported. The outbreak was associated with Rickettsia rickettsii in an unexpected tick vector, the brown dog tick (Rhipicephalus sanguineus), which had not been previously associated with RMSF transmission in the United States. We investigated the extent of exposure to R. rickettsii in the local area through serologic evaluations of children and dogs in 2003-2004, and in canine sera from 1996. Antibodies to R. rickettsii at titers > or = 32 were detected in 10% of children and 70% of dogs in the outbreak community and 16% of children and 57% of dogs in a neighboring community. In comparison, only 5% of canine samples from 1996 had anti-R. rickettsii antibodies at titers > or = 32. These results suggest that exposures to RMSF have increased over the past 9 years, and that RMSF may now be endemic in this region.
在2002年至2004年期间，亚利桑那州一个此前未报告过落基山斑疹热（RMSF）的农村社区发现了15例落基山斑疹热患者。此次疫情与立氏立克次体有关，传播媒介是一种意想不到的蜱虫——褐犬蜱（血红扇头蜱），此前在美国它并未与落基山斑疹热的传播相关联。我们通过对2003 - 2004年当地儿童和犬类以及1996年犬类血清进行血清学评估，调查了当地立氏立克次体的暴露程度。在疫情社区，10%的儿童和70%的犬类检测到抗立氏立克次体抗体，效价≥32；在相邻社区，16%的儿童和57%的犬类检测到该抗体。相比之下，1996年的犬类样本中只有5%的抗立氏立克次体抗体效价≥32。这些结果表明，在过去9年里落基山斑疹热的暴露情况有所增加，且该地区现在可能存在落基山斑疹热地方病。
Zotero 插件