Moreno-Jiménez Bernardo, López Blanco Balbina, Rodríguez-Muñoz Alfredo, Garrosa Hernández Eva
Department of Biological and Health Psychology, Faculty of Psychology, Autonomous University of Madrid, Madrid, Spain.
J Psychosom Res. 2007 Jan;62(1):39-46. doi: 10.1016/j.jpsychores.2006.07.026.
The aim of the study was to examine the influence of personality factors on health-related quality of life (HRQOL) in patients with inflammatory bowel disease (IBD).
A total of 120 individuals, 60 with ulcerative colitis and 60 with Crohn's disease, filled out the Inflammatory Bowel Disease Questionnaire, the Rosenberg Self-Esteem Scale, the Neuroticism scale of the Eysenck Personality Inventory, and a scale about difficulty describing feelings to other people. Sociodemographic and clinical information was also collected.
Results of hierarchical regression analysis, after controlling for possible confounder effects of demographic and clinical variables, showed the predictive power of the block of personality variables, accounting for significant amounts (13-22%) of variance across the four HRQOL measures. Except for self-esteem, which was the factor most closely related to social functioning, neuroticism seemed to be the most closely related to the four indicators of quality of life. It was also found that greater difficulty in describing feelings was linked to poorer HRQOL.
In summary, some personality factors are useful for understanding the process of HRQOL in patients with IBD. Recognizing these differences may enrich clinical research and may be crucial when designing interventions aimed at treatment effectiveness.
本研究旨在探讨人格因素对炎症性肠病（IBD）患者健康相关生活质量（HRQOL）的影响。
共有120名个体参与研究，其中60例患有溃疡性结肠炎，60例患有克罗恩病。他们填写了炎症性肠病问卷、罗森伯格自尊量表、艾森克人格问卷神经质分量表以及一个关于向他人描述感受困难程度的量表。同时还收集了社会人口学和临床信息。
在控制了人口统计学和临床变量可能的混杂效应后，层次回归分析结果显示人格变量组具有预测能力，在四项HRQOL测量指标中解释了相当比例（13 - 22%）的方差变异。除了自尊是与社会功能最密切相关的因素外，神经质似乎与生活质量的四项指标关系最为密切。研究还发现，描述感受的困难程度越大，HRQOL越差。
总之，一些人格因素有助于理解IBD患者的HRQOL过程。认识到这些差异可能会丰富临床研究，并且在设计旨在提高治疗效果的干预措施时可能至关重要。
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